News

[New Paper]SET-LRP in the Neoteric Ethyl Lactate Alcohol

A new paper from the group has been published in Biomacromolecules. The paper reports  that ethyl lactate is an excellent solvent for the Cu(0) wire-catalyzed SET-LRP to produce both hydrophilic and hydrophobic polyacrylates that exhibit precise chain end functionality.

[New Paper]Searching for efficient SET-LRP systems via biphasic mixtures of water with carbonates, ethers and dipolar aprotic solvents

A new paper from the group has been published in Polymer Chemistry. The paper reports a series of screening experiments on biphasic mixtures of water with linear diethyl and dimethyl carbonates, cyclic propylene and ethylene carbonates, the cyclic ethers THF and dioxane, and with dipolar aprotic solvents.

[New Paper]SET-LRP Platform to Practice, Develop and Invent

Another Perspective from the group has been published in BiomacromoleculesThis paper helps experts and non-expert practice, develop and invent new concepts and methodologies for SET-LRP in order to advance its status and the status of other living radical polymerization methods to the level of the most precise living polymerization methods.

[New Paper]Janus dendrimersomes coassembled from fluorinated, hydrogenated, and hybrid Janus dendrimers as models for cell fusion and fission

A new paper from the group has been published in PNAS. The paper reports  the discovery of an unprecedented class of JPs denoted Janus dendrimersomes (JDSs) coassembled from amphiphilic Janus dendrimers (JDs) with fluorinated, hydrogenated, and hybrid fluorinated–hydrogenated hydrophobic chains.

[New Paper] Demonstrating the 81-Helicity and Nanomechanical Function of Self-Organizable Dendronized Polymethacrylates and Polyacrylates

A new paper from the group has been published in Macromolecules. The paper reports  the synthesis of six dendronized polymers synthesized via single-electron transfer living radical polymerization (SET-LRP) of self-assembling dendrons with a methacrylate or acrylate apex.

[New Paper] Ultrafast SET-LRP with Peptoid Cytostatic Drugs as Monofunctional and Bifunctional Initiators

A new paper from the group has been published in Biomacromolecules. The paper reports  the developement of novel peptoid-type initiators such as 1,4-bis(2-bromopropionyl)piperazine and 4-(2-bromopropionyl)morpholine in order to continue expanding the use of Single Electron Transfer-Living Radical Polymerization (SET-LRP) in applications at the interface between macromolecular science, biomacromolecules, biology and medicine.

[In the Press] Stirring rate-dependent SET-LRP paper featured on Front Cover

The group's recent publication reporting the stirring rate dependence of interfacial SET-LRP of methyl acrylate (MA) and butyl acrylate (BA), has been featured on the front cover of Polymer Chemistry.

Samuel E. Sherman is acknowledged for helping the authors produce the cover image.

[New Paper] Stirring rate provides dramatic acceleration of the ultrafast interfacial SET-LRP in biphasic acetonitrile-water mixtures

A new paper from the group has been published in Polymer Chemistry. The paper reports a dramatic accelaration of the already ultrafast interfacial SET-LRP of methyl acrylate (MA) and butyl acrylate (BA) in the biphasic mixtures containing the non-disproportionation solvent acetonitrile with water. 

[Former Member News] Daniela Wilson Promoted to Full Professor

We are delighted to learn that former group member, Daniela A. Wilson, has been promoted to the position of Professor at Radboud University, Nijmegen, The Netherlands, where she now also chairs the Department of Systems Chemistry. Daniela spent three years in the group as a postdoctoral research associate (2007–2010), after which she joined Radboud University as a Research Associate. Daniela was quickly promoted to Assistant Professor (2012) and now to Professor.

[New Paper] Acetone-water biphasic mixtures as solvents for ultrafast SET-LRP of hydrophobic acrylates

A new paper from the group has been published in Polymer Chemistry. The paper reports the elaboration of acetone-water biphasic mixtures as solvents for ultrafast single electron transfer living radical polymerization (SET-LRP) that provides close to 100% conversion of methyl and n-butyl acrylates to the corresponding polymers with near quantitative chain-end functionality in 20 to 35 min reaction time at room temperature.

[New Paper] Mimicking Complex Biological Membranes and Their Programmable Glycan Ligands with Dendrimersomes and Glycodendrimersomes

A  Review from the group has been published in Chemical Reviews. The paper covers all aspects of the synthesis of amphiphilic Janus dendrimers (JDs) and glycodendrimers (JGDs) and their biological activity and applications after assembly in aqueous media.

[New Paper] Recent Developments in the Synthesis of Biomacromolecules and their Conjugates by Single Electron Transfer–Living Radical Polymerization

A Perspective from the group has been published in Biomacromolecules. The paper highlights the recent advances of SET-LRP in the synthesis of biomacromolecules and their conjugates.  The paper has also been selected as an ACS Editors' Choice article, and is highlighted on ACS Publications' website.

[In the Press] Dendrimers with Self-Interrupting Synthesis Highlighted by Penn News

The group's recent work on the self-interrupting synthesis of polyamide dendrimers, published in March in Proceedings of the National Academy of Sciences, has been highlighted in an article by Penn News, entitled 'Penn Researchers Push the Limits of Organic Synthesis'. Read the article here.

[New Paper] Self-Interrupted Synthesis of Sterically Hindered Aliphatic Polyamide Dendrimers

A new paper from the group has been published in Proceedings of the National Academy of Sciences. The paper reports a series of sterically crowded aliphatic polyamide dendrimers whose reactivity ceases upon reaching a certain generation. This generation - 4, 5 or 6 - is dictated not by the core multiplicity, as expected, but rather by the conformation of the dendrimer core. This results in a self-termination of the synthesis of higher generation dendrimers, as previously predicted by Nobel Laureate Pierre-Gilles de Gennes.

[New Paper] A Tetragonal Phase Self-Organized from Unimolecular Spheres Assembled from a Substituted Poly(2-oxazoline)

A new paper from the group has been accepted for publication in Macromolecules. The paper reports the discovery of a tetragonal phase self-organized from a dendronized poly(2-oxazoline). This dendronized polymer organizes into columnar hexagonal, Pm3n cubic and tetragonal phases as a function of temperature and degree of polymerization.