Room 326 Leidy Labs
My research is focused on the evolutionary ecology of vector-borne diseases. I strive to understand how the environment influences populations of vectors and diseases and how the interactions among them are shaped. Specifically, I study the epidemiology, population dynamics, and history of complex diseases systems from an ecological perspective..
My research is holistic in nature, and consequently, I utilize a wide-range of tools. I use analytical and stochastic models to understand patterns of occurrence and prevalence of diseases. I integrate phylogenetic and population genetic tools together with geographical information systems to take into account the inherent temporal and spatial heterogeneity often present in complex systems. This integration allows me to investigate the demography, phylogeography, and history of disease vectors in different environments. I also use experimental approaches to uncover the evolutionary ecology of vector diseases. Recently, I have been expanding my analytical toolbox to include newly developed next generation sequencing technologies.
Recent publications in the lab
Khatchikian, CE, Nadelman RB, Nowakowski J, Schwartz I, Wormser GP, Brisson D. 2014. Evidence for strain-specific immunity in patients treated for early Lyme disease. Infection and Immunity 82:1408-1413.
Foley, EA, Khatchikian CE, Hwang J, Ancca-Juárez J, Borrini-Mayori K, Quıspe-Machaca VR, Levy MZ, Brisson D. 2013. Population structure of the Chagas disease vector, Triatoma infestans, in an urban environment. Molecular Ecology. 22:5162–5171. Abstract
Khatchikian, CE, Prusinski M, Stone M, Backenson PB, I.N. Wang, M.Z. Levy, Brisson D. 2012. Contemporary population expansion of blacklegged Ticks (Ixodes scapularis). Ecosphere. 3:10. Abstract